Endocrine Abstracts

Objective: Opioids are among the most commonly used symptomatic treatments of somatoform pain disorder. Human and animal studies suggest that chronic exposure to opioids suppresses the hypothalamo-pituitary-adrenal (HPA) and the hypothalamic-pituitary-gonadal axis. We report on a rare case of secondary adrenal failure and secondary amenorrhea due to hydromorphone treatment.Case report: A 32-year-old female patient presented with fatigue, weakness, orthos...